Following a brief rain delay, the two sides finally met for the first time on the pitch. The Gunners struck early when Gabriel Martinelli found the back of the net in the fifth minute, but the Lions answered later in the first half with a sensational goal from Facundo Torres.
Torres brought down a gorgeous pass from Antonio Carlos and kept his composure by finding his footing, cutting on his left foot and firing the ball past a diving Aaron Ramsdale.
The Arsenal was backed by two goals in the second half coming from Eddie Nketiah and Reiss Nelson to seal the victory for the London-based side.
The match saw a plethora of players enter the match with each side allowed 10 substitutions each, including OCB product Moises Tablante earning his first minutes with the senior side. Nineteen-year-old Homegrown Mikey Halliday earned the start at right back, playing 63 minutes in the match.